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Hair Loss Open Topic

What are the causes, symptoms and treatment for Diffused Unpatterned Alopecia (DUPA)

Diffused Unpatterned Alopecia (DUPA) is a type of androgenic alopecia or genetic hair loss. Diffused Unpatterned Alopecia (DUPA) can affect both men and women. In this article, we discuss the causes, symptoms and treatment of Diffused Unpatterned Alopecia (DUPA).

Causes: Diffused Unpatterned Alopecia is a subtype of androgenic alopecia.  Both men and women produce Testosterone which converts in to Dihydrotestosterone the main catalyst for genetic hair loss. Hair follicles, as well as the sebaceous glands, contain high levels of an enzyme called 5-alpha-reductase. This enzyme converts testosterone into DHT, via the blood. The difference between male pattern and female pattern hair loss is that Diffused Unpatterned Alopecia (DUPA) does not follow any pattern. Therefore, the back and sides of the scalp may be susceptible to thinning.

Symptoms: The most common symptom of Diffused Unpatterned Alopecia (DUPA) is a diffuse thinning over the entire sclap. Unlike Diffused Patterned Alopecia (DPA), DUPA lacks the stable permanent zone associated with other forms of alopecia. DUPA is defined as a general decrease in the density of hair without any definite pattern.

Treatment: As a subtype of androgenic alopecia or genetic hair loss Difussed Unpatterned Alopecia (DUPA) is typically treated with the same medications as Diffused Patterned Alopecia (DPA). There are currently two FDA approved medications that prevent and slow the progression of androgenic alopeica otherwise known as genetic hair loss, the medications are Propecia (finasteride)  and Rogaine (minoxidil). Both medications have been proven to stop and even regrow hair in some patients suffering from genetic hair loss.  Hair transplant surgery is typiocally not an option for DUPA as there is no stable area of the scalp where hair doesn't thin out.


Anyone suffering from diffused hair loss should consult with a dermatologist or hair restoration surgeon for a proper diagnosis. This is especially true for any male or female considering hair restoration. The treatments avaialble today can improve the quality and density of any individual suffering from Diffused Unpatterned Alopecia (DUPA). 

Written and Published By,

Melvin (HTsoon), Editorial Assistant and Forum Co-Moderator