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Hair Loss Treatments

Exosome Therapy Is It The Hair Loss Cure We've Been Waiting For?

The hair loss industry is worth 3.9 billion dollars, and this figure continues to climb each year. Each year there is a new treatment that is promised to stop hair loss and regrow hair without side effects and for a reasonable cost. Some may remember the supposed 'hair loss cure 2020', it's now 2020 in a few months, and there seems to be no cure in sight, or is there? In this article, we will be discussing exosome therapy as a possible treatment for hair loss. 

What Are Exosomes?

Exosomes are small lipid vesicles that are discharged by different cells, which contain several molecules such as microRNA (miRNA). miRNA regulates bodily functions through gene management- exosomes direct cell-to-cell signaling. 

Exosome Therapy For Hair Loss

We've all heard about stem cell therapy, which was thought to be the next significant treatment for stopping hair loss. Stem cells were supposed to cure everything from a backache to hair loss, but that hasn't happened at all. Let's talk about exosome therapy, is the hype valid? Well, let's discuss it.

Exosomes are like pollen that come off of flowers, except they come off the walls of your cells. They perform a variety of functions, which include building cells and delivering signals. Scientists believe that when these exosomes contain several growth factors, as well. When physicians inject these exosomes into the scalp along with Mesenchymal Stem Cells (MSCs), some physicians believe they will regenerate the hair follicles on the scalp. 

What Do The Studies Say

There isn't a lot of clinical data surrounding exosome treatment. Still, there was one study in 2017 that found that exosomes derived from human dermal papilla cells promote hair growth in cultured human hair follicles.  Dermal papillae (DP) are essential for hair growth and regeneration. Also, the study found that injecting exosomes directly into mice induced the anagen (growth) phase from the telogen (resting) phase, and the anagen phase was prolonged. 

Our Final Thoughts

Some of the studies seem promising, but we have to remember that inducing hair growth, doesn't mean that DHT will no longer attack the hair. A genetic vulnerability causes male and female pattern hair loss to the hormone called DHT. From what we can see, these exosomes will do nothing to stop DHT from attacking the hair follicles. 

However, given the fact that exosomes induced the anagen phase in mice, it makes it appealing to add in conjunction with a hair transplant. As we all know, waiting for the transplanted hair to grow is one of the most frustrating aspects of undergoing surgical hair restoration. If a hair transplant surgeon can inject exosomes into the scalp to induce faster hair growth, that would be something to look for soon.  As of now, we see no reason to start throwing Propecia and Rogaine bottles away just yet.