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Hair Loss Treatments

Is Clasceterone CB-03-01 The Hair Loss Cure We've Been Waiting For?

Clasceterone is known as the hair loss cure online, also goes by the name CB-03-01 and Breezula on the internet by hair loss sufferers. There's been a lot of hype surrounding Clasceterone, similar to the hype around RU58841. Except this drug has gotten FDA approval as of August 2020. However, it hasn't been approved for hair loss, at least not yet. In this article, we will be discussing the possible treatment, side effects, and safety of Clasceterone (CB-03-01). 

Will Clasceterone Be A Hair Loss Cure?

Clasceterone (CB-03-01) is a potent anti-androgen that inhibits androgens locally on the scalp. In theory, inhibiting androgens such as DHT locally instead of systemically will significantly reduce side effects. Genetic hair loss occurs because the androgen DHT binds to vulnerable androgen receptors on the scalp. These susceptible hair follicles gradually shrink until they no longer grow -this process is called miniaturization or balding. A hair loss cure would revolutionize the hair loss industry, but the research shows a hair loss cure is unlikely any time soon. 

Clascaterone will keep DHT from binding to the androgen receptors on the scalp, without eliminating DHT in the body. There is a lot of controversy surrounding drugs like Propecia (finasteride) because there have been thousands of reports of the drug causing permanent sexual dysfunction, as well as other cognitive issues.

Positive Results in Clinical Trials

In the most recent clinical trials, 400 men from ages 18 to 55 participated in a study that examined dosages and hair count. Unlike finasteride, the higher dosage saw better results. The controlled trial also included a placebo group. Researchers haven't touted Clasceterone or Breezula as a hair loss cure, as it is reported online in hair loss forums, etc. 

Researchers reviewed essential factors in all four groups.  The researchers examined whether the hair loss stopped in these groups, how much hair regrew, and the overall hair thickness.  There were four dosages, 2.5 % applied twice daily, 5 % applied twice daily, 7.5 % applied once daily, and 7.5 % applied twice daily. 

All four groups saw a reduction in the progression of their male pattern baldness. However, there was a significant difference in the improvement of the groups that received 5 % and 7.5%. The results were reasonably quick, with participants seeing a difference within three months. 

The participant's hair thickness wasn't impacted, except the group that received 7.5 % applied twice daily, and results were not evident until six months. The other groups did see an improvement in hair thickness, but it took them an additional six months to see the difference. 

To date, there have been no sexual side effects reported in any of the studies, and no changes in libido. Clascaterone does not interfere with the hormonal profile. There haven't been as many studies as there have been for medications like finasteride or dutasteride. But the clinical trials that exist are promising.


The studies are impressive, and the fact that the drug doesn't have any adverse reactions in any of the clinical trials is exciting. However, it will not cure hair loss by any means. It does slow and even stops hair loss in some cases, but its not a hair loss cure. The drug has been approved by the FDA as of August 2020 to treat acne. There's a good chance that the drug will be authorized to treat androgenic alopecia. To date, the only method to regrow hair on a bald scalp is through hair transplant surgery. To schedule a free consultation with a pre-screened surgeon in your area, click here.