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Hair Loss Treatments

Peptide Found In Japanese Water Chestnut May Reverse Hair Loss

The Trapa Japonica (Japanese water chestnut) fruit grows naturally in ponds and lakes, and its benefits treat a variety of ailments, including hair loss. A new study found that this fruit can reverse the effects of DHT in the human dermal papilla cells. In this article, we will be discussing Japanese water chestnut as a possible treatment for hair loss.

What Causes Hair Loss

There are several forms of hair loss, but the most common type is called androgenic alopecia or genetic hair loss. A genetic vulnerability causes hereditary hair loss to the hormone called DHT. DHT binds to the vulnerable hair follicles receptor sites, and slowly begins to shrink the hair follicles until they no longer grow- this process is called miniaturization or thinning.  

How Does Japanese Water Chestnut Stop Hair Loss?

A recent study conducted in South Korea suggests that the Japanese water chestnut has a positive effect on hair loss and removes DHT, a harmful hormone from the dermal papilla cells. Dermal papilla cells regulate hair follicle development and growth; with the removal of DHT, hair loss will subside.

Earlier this year, Hairclone announced it plans to clone human dermal papilla cells (DPC). Still, according to this new study, the Japanese water chestnut may naturally increase the production of DPC's. Who needs cloning when you can do it the natural way. 

What Did The Study Say?

The fruit Trapa Japonica was refined and separated into a peptide from the ferment in the study. This process includes expensive and complicated fermentation and separation processes, which is not available to the general public. Researchers measured Cytotoxic activity levels in treated DPC's. 

Researchers treated cells with 1mg/1ml of DHT. These cells showed degradation, and DHT suppressed cell proliferation. However, cells that were both treated with DHT 1mg/ml, and the Peptide AC 2 did not suffer any degradation or suppressed proliferation. 


Sadly, this peptide isn't available to the general public, and even Japanese water chestnut is challenging to find online. But perhaps this study will validate hair loss supplement companies to start investigating this as a potential treatment. To date, the most effective treatment for hair loss is surgical hair restoration